Evidence Browser: Source: MooreEtAl2014

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Publication:Hyperfibrinolysis, physiologic fibrinolysis, and fibrinolysis shutdown: the spectrum of postinjury fibrinolysis and relevance to antifibrinolytic therapy
Reference:

Moore HB, Moore EE, Gonzalez E, et al. Hyperfibrinolysis, physiologic fibrinolysis, and fibrinolysis shutdown: the spectrum of postinjury fibrinolysis and relevance to antifibrinolytic therapy. J Trauma Acute Care Surg 2014;77:811-7; discussion 7.

Abstract:None
Publication Type:Human observational study
Low Risk of Bias:
  • All eligible patients included
  • Baseline characteristics of sample
  • Coagulopathy appropriately defined
  • Eligibility criteria
  • Representative sample from a relevant population
High Risk of Bias:
  • Adjustment for confounding
  • Causative factors defined
  • Coagulopathy assessed on arrival to hospital
Unclear Risk of Bias:
  • Causative factors measured accurately
Risk of Bias Score:5