Evidence Browser: Source: JohanssonEtAl2011b

Main Page

Variables

Relations

Fragments

Data

Experts

Publications

Publication:A high admission syndecan-1 level, a marker of endothelial glycocalyx degradation, is associated with inflammation, protein C depletion, fibrinolysis, and increased mortality in trauma patients
Reference:

Johansson PI, Stensballe J, Rasmussen LS, Ostrowski SR. A high admission syndecan-1 level, a marker of endothelial glycocalyx degradation, is associated with inflammation, protein C depletion, fibrinolysis, and increased mortality in trauma patients. Ann Surg 2011;254:194-200.

Abstract:None
Publication Type:Human observational study
Low Risk of Bias:
  • Baseline characteristics of sample
  • Causative factors defined
  • Causative factors measured accurately
  • Coagulopathy appropriately defined
  • Coagulopathy assessed on arrival to hospital
  • Eligibility criteria
  • Representative sample from a relevant population
High Risk of Bias:
  • Adjustment for confounding
Unclear Risk of Bias:
  • All eligible patients included
Risk of Bias Score:7