Evidence Browser: Source: CohenEtAl2012

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Publication:Critical role of activated protein C in early coagulopathy and later organ failure, infection and death in trauma patients
Reference:

Cohen MJ, Call M, Nelson M, et al. Critical role of activated protein C in early coagulopathy and later organ failure, infection and death in trauma patients. Ann Surg 2012;255:379-85.

Abstract:None
Publication Type:Human observational study
Low Risk of Bias:
  • All eligible patients included
  • Baseline characteristics of sample
  • Causative factors defined
  • Causative factors measured accurately
  • Coagulopathy appropriately defined
  • Coagulopathy assessed on arrival to hospital
  • Eligibility criteria
  • Representative sample from a relevant population
High Risk of Bias:
  • Adjustment for confounding
Risk of Bias Score:8