Publication: | Excess lactate: An index of reversibility of shock in human patients | ||
Reference: | Excess Lactate: An Index of Reversibility of Shock in Human Patients. Science. 1964 Mar 27;143(3613):1457-9 | ||
Abstract: | "Excess lactate," an indicator of oxygen debt, has been studied as a metabolic index of severity of the shock state in human patients. The levels of excess lactate correspond to severity of circulatory failure, and an excess of more than 4 millimoles per liter prognosticates a fatal outcome. The validity of this index was confirmed by studies on experimental hemorrhagic shock in dogs. It provides a parameter for measurement of "reversibility" and serves as an objective clinical guide. | ||
Publication Type: | None | ||
Risk of Bias Score: | None |