Evidence Browser: Source: JohanssonEtAl2012

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Publication:High sCD40L levels early after trauma are associated with enhanced shock, sympathoadrenal activation, tissue and endothelial damage, coagulopathy and mortality
Reference:

Johansson PI, Sorensen AM, Perner A, et al. High sCD40L levels early after trauma are associated with enhanced shock, sympathoadrenal activation, tissue and endothelial damage, coagulopathy and mortality. J Thromb Haemost 2012;10:207-16.

Abstract:None
Publication Type:Human observational study
Low Risk of Bias:
  • Baseline characteristics of sample
  • Coagulopathy appropriately defined
  • Coagulopathy assessed on arrival to hospital
  • Eligibility criteria
  • Representative sample from a relevant population
High Risk of Bias:
  • Adjustment for confounding
  • All eligible patients included
  • Causative factors defined
  • Causative factors measured accurately
Risk of Bias Score:5