Evidence Base for TIC BN Evidence-Base

Evidence Browser: Relation: Tissue_Injury → TIC

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Relation:	Tissue_Injury→ TIC
Evidence:	ATC occurs after severe tissue injury [References] CohenEtAl2013 Tissue injury measured by Injury Severity Score (ISS) is correlated with PT-based (0.14, p< 0.001) and PTT-based coagulopathy (0.23, p<0.001) [References] CohenEtAl2013 Coagulopathy is associated with combination of tissue hypoperfusion and tissue injury in a mice model [References] CheseboroEtAl2009 Coagulopathy developed in rats subjected to haemorrhagic shock and tissue perfusion. [References] FrithEtAl2010 Tissue injury, measured by Injury Severity Score (ISS), is strongly associated with coagulopathy. [References] BrohiEtAl2003 BrohiEtAl2007b BrohiEtAl2008 CohenEtAl2013 CosgriffEtAl1997 MaegeleEtAl2007 NilesEtAl2008 WafaisadeEtAl2010 Patients with severe tissue injury but no physiologic derangement rarely present with a coagulopathy. Tissue trauma is, therefore, an initiator of coagulation, but in isolation is rarely responsible for clinical coagulopathy. [References] Brohi2009 BrohiEtAl2007a SpahnEtAl2013 Tissue injury activates the clotting cascade by exposing tissue factor to blood and producing thrombin.488,489 By definition, all trauma patients have some degree of tissue injury. The extent depends on the mechanism of injury, the amount of energy transferred, and the proportion of the body involved [References] BrohiEtAl2003 BrownEtAl2013 CapEtAl2011 CarrickEtAl2005 ChaiEtAl2013 CheddieEtAl2013 ChenEtAl2017 CheseboroEtAl2009 ChhabraEtAl2013 ChoEtAl2009 CohenEtAl2009 CohenEtAl2010 CohenEtAl2012 CohenEtAl2013 CosgriffEtAl1997 DarlingtonEtAl2013 DarlingtonEtAl2015 DavisEtAl1996 DerasEtAl2014 DuanEtAl2014 DunbarEtAl2009 FloccardEtAl2012 FrithEtAl2010 GenetEtAl2013 GrottkeEtAl2010 HagemoEtAl2013 HarrEtAl2011 HayakawaEtAl2013 HayakawaEtAl2015 HulkaEtAl1996 JohanssonEtAl2011 JohanssonEtAl2011b JohanssonEtAl2012 JohanssonEtAl2013 KapschEtAl1984 KhanEtAl2014 KlemckeEtAl2005 KutcherEtAl2013 LeeEtAl2014 LozanceEtAl1998 LustenbergerEtAl2010 LustenbergerEtAl2013 MacLeodEtAl2014 MaegeleEtAl2007 MatijevicEtAl2014 MayEtAl1997 MitraEtAl2011 MooreEtAl2014 NealEtAl2014 NekludovEtAl2007 NilesEtAl2008 OstrowskiEtAl2011 OstrowskiEtAl2012 PratEtAl2015 RazaEtAl2013 RizoliEtAl2011 RizoliEtAl2011b ShazEtAl2011 SimmonsEtAl2011 SixtaEtAl2012 SpronkEtAl2015 TalvingEtAl2009 TongletEtAl2014 TurtayEtAl2010 WafaisadeEtAl2010b WattsEtAl2015 WhiteEtAl2010 WhiteEtAl2011 WhiteEtAl2015 WhiteEtAl2015b WindelovEtAl2014 XuEtAl2013 XuEtAl2015a XuEtAl2015b vanZylEtAl2016