Evidence Base for TIC BN Evidence-Base

Relation:	Tissue_Perfusion→ Base_Excess
Evidence:	Base deficit accurately reflects the tissue perfusion changes according to haemorrhagic shock in a pig model. Lactate correlates closely with base deficit/excess. [References] DavisEtAl1994 The degree of metabolic acidosis may be measured by serum base deficit. [References] WilliamsEtAl2013 Admission base deficit / excess is a clinically useful early marker of tissue hypoperfusion in trauma patients. [References] DavisEtAl1991 DavisEtAl1996 RutherfordEtAl1992 SpahnEtAl2013 Increasing base deficit, as a marker of hypooperfusion, is significantly associated with coaguloapthy. [References] BrohiEtAl2007b BrohiEtAl2008 CohenEtAl2013 FrithEtAl2010 SimmonsEtAl2011 WafaisadeEtAl2010

TIC BN Evidence-Base