Evidence Browser: Source: CohenEtAl2009

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Publication:Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusion
Reference:

Cohen MJ, Brohi K, Calfee CS, et al. Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusion. Crit Care 2009;13:R174.

Abstract:None
Publication Type:Human observational study
Low Risk of Bias:
  • All eligible patients included
  • Baseline characteristics of sample
  • Coagulopathy appropriately defined
  • Coagulopathy assessed on arrival to hospital
  • Eligibility criteria
  • Representative sample from a relevant population
High Risk of Bias:
  • Adjustment for confounding
  • Causative factors defined
Unclear Risk of Bias:
  • Causative factors measured accurately
Risk of Bias Score:6