Evidence Browser: Relation: Tissue_Perfusion → pH

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Relation: Tissue_Perfusion→ pH
Evidence:
  • Lactic acidosis results from tissue hypoxia resulting from hypoperfusion. Cells undergoing anaerobic respiration generate lactic acid. The degree of lactic acidosis is a sensitive measure of the degree of shock / tissue hypoperfusion.
    [References]
  • Increasing severity of shock (worsening tissue hypoperfusion) is associated with increasing heart rate (HR), worsening hypotension and worsening metabolic acidosis.
    [References]