Evidence Base for TIC BN Evidence-Base

Evidence Browser: Relation: Tissue_Perfusion → TIC

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Relation:	Tissue_Perfusion→ TIC
Evidence:	Hypoperfusion appears to be a primary driver of trauma coagulopathy. Acute traumatic coagulopathy is only evident in the presence of tissue hypoperfusion [References] Brohi2009 BrohiEtAl2007a BrohiEtAl2007b BrohiEtAl2008 CohenEtAl2013 FrithEtAl2010 HessEtAl2008 SimmonsEtAl2011 SpahnEtAl2013 WafaisadeEtAl2010 Coagulopathy is associated with combination of tissue hypoperfusion and tissue injury in a mice model [References] CheseboroEtAl2009 Coagulopathy developed in rats subjected to haemorrhagic shock and tissue perfusion. [References] FrithEtAl2010 Patients with severe tissue injury but no physiologic derangement rarely present with a coagulopathy. Tissue trauma is, therefore, an initiator of coagulation, but in isolation is rarely responsible for clinical coagulopathy. [References] Brohi2009 BrohiEtAl2007a SpahnEtAl2013 Tissue hypoperfusion appears to cause coagulopathy by activation of anticoagulant and fibrinolytic pathways. [References] BrohiEtAl2007b BrohiEtAl2008 BrownEtAl2012 BrownEtAl2013 CapEtAl2011 CharbitEtAl2016 CheddieEtAl2013 ChenEtAl2017 CheseboroEtAl2009 ChoEtAl2009 CohenEtAl2007 CohenEtAl2009 CohenEtAl2012 CohenEtAl2013 CosgriffEtAl1997 DarlingtonEtAl2011 DarlingtonEtAl2013 DarlingtonEtAl2015 DavisEtAl1996 DerasEtAl2014 DoranEtAl2012 DuanEtAl2014 FerraraEtAl1990 FrithEtAl2010 FungEtAl2012 HagemoEtAl2013 HarrEtAl2011 HayakawaEtAl2011 IwamotoEtAl2010 JansenEtAl2011 JohanssonEtAl2012b KapschEtAl1984 KutcherEtAl2013 LeeEtAl2014 LetsonEtAl2012 LetsonEtAl2016 LustenbergerEtAl2010 MartiniEtAl2005b MartiniEtAl2006b MartiniEtAl2008 MartiniEtAl2013 MatijevicEtAl2014 MitraEtAl2011 NealEtAl2014 NishiEtAl2013 ParkEtAl2013 RazaEtAl2013 RezendeNetoEtAl2014 SchochlEtAl2013 SimmonsEtAl2011 SixtaEtAl2012 TalvingEtAl2009 TongletEtAl2014 TorresEtAl2013 WafaisadeEtAl2010 WafaisadeEtAl2010b WattsEtAl2015 WhiteEtAl2010 WhiteEtAl2011 WhiteEtAl2015 WhiteEtAl2015b XuEtAl2013 XuEtAl2015b vanZylEtAl2016